With the promotion of new urbanization, the proportion of prefabricated steel structure buildings has increased year by year. However, the existing steel structure systems applied in rural buildings face problems such as poor living quality, low level of components standardization, inconvenient transportation and installation, low construction quality, and serious pollution and waste. It is urgent to develop low-cost, simple-constructed, ecological prefabricated light steel structure systems residence and corresponding construction technologies. The light steel frame-grid wall structure not only has the advantages of excellent seismic performance, light components and easy transportation, but also can be wholly connected by bolts or self-tapping screws, which is convenient for installation. In order to study the simple construction technology and lateral performance of this structure, a single-story house with a steel frame-steel, wood and bamboo grid wall hybrid structure system wholly connected by screws was built, and its in-situ experiment was carried out. Taking a light steel frame-steel grid wall in this project as an example, this paper expounds the simple construction technology of the light steel frame-steel grid wall from the column base, foundation, installation of frame and steel gird, and fixing of wallboard, and its lateral performance was obtained through the in-situ static experiment. The research shows that the light steel frame-steel grid wall is easy to install, which can save manpower and material resources, and is suitable for application in rural areas, and the lateral performance of the light steel frame-steel grid wall with this construction technology can meet the design requirements.